Candida albicians is part of the normal gut micro biome in humans, but when is out of balance it can cause infection. It is common to be used antifungal medication but recent study implies that coconut oil might be effective as well. Prof. Carol Kumamoto, PhD, from Tufts University in Massachusetts made the research and publishes the story in the American Society for Microbiology’s journal sphere.
There are certain types of people that are more often affected of this infection like those with compromised immune system- cancer patients, transplant patients, premature infants and sometimes elderly people. In these patients candida albicans can leave the gut and to enter in the bloodstream. Therefore to cause infection this in some case could be deadly. It affects the liver, kidneys, lungs, and spleen, brain and heart valves.
Nearly half of the patient with systematic Candida albicans infection will die.
People who get this disease are very sick and generally in the hospital,” says Prof. Kumamoto. “Candida is one of the most common causes of bloodstream infections in hospitalized patients.”
Although the current first line of defense is to use antifungal drugs, the researchers explain that they can contribute to the emergence of drug-resistant strains, so clinicians are cautious about using them.
Previous in vitro studies have shown that coconut oil has antifungal properties; because changes in the amount and type of fat can alter gastrointestinal microbiota, the team designed an experiment involving different high-fat diets and their effect on the guts of mice.
All groups of mice were fed these diets for 14 days before the researchers inoculated them with C. albicans, and they continued on their respective diets for 21 more days.
Results showed that 21 days after the inoculation, the mice that were fed the coconut oil diet had C. albicans colonization in their stomachs that was significantly lower than the mice that were fed the beef tallow diet, the soybean oil diet or the standard diet.
In a further experiment, she and her team switched the mice on the beef fat diet to the coconut oil diet and found that just 4 days after the diet change, “the colonization changed so it looked almost exactly like what you saw in a mouse that had been on coconut oil the entire time.”
She clarifies that they might want to figure out the instrument behind how coconut oil delivers these impacts and whether these outcomes can be repeated in people.
In the event that all works out as expected, the exploration group will dispatch a clinical trial including hospitalized newborn children who are at high hazard for systemic candidiasis and how coconut oil may offer assistance.